The SCTO Forum 2025, held on January 29th in Bern, addressed important updates to the ICH GCP E6(R3) Guidelines, aiming to improve flexibility, efficiency, and data integrity in clinical trials. Seventy-seven people attended this engaging event. The presentations covered the rationale behind the revisions, real-world evidence, and quality by design.

Key findings:

• Continuous reflection is essential for decision-making.
• Researchers must familiarize themselves with both the GCP E6 and the E8 guidelines.
• The revisions provide sufficient preparation time and aim to improve the practice of clinical trials.

Learn more about the SCTO Forum and download the presentations here.